A visual artist born in 1975 in Rafah, Gaza, Khaled graduated with a bachelor’s degree in art education from Al-Aqsa University in 1999. Since then, he has become an active figure in the Palestinian art scene, both as an artist and as a founding member of the Kayan Contemporary Arts Group. Throughout his career, Khaled has focused on exploring contemporary artistic tools and techniques, particularly in sculpture, installations, and drawing. He uses these mediums to express complex emotions and universal themes, delving into the psychological and emotional depth of human experience.

One of Khaled’s most significant solo exhibitions, I Miss You So Much, featured his sculptural works and was showcased at both Shababeek Gallery↗  in Gaza and Gallery 28 in Rafah, where it was well received. In this exhibition, Khalid addressed the issue of people with amputated limbs as a result of the Israeli occupation’s brutal suppression of the Great Return March in Gaza, which targeted many peaceful young men and boys in their limbs. Regarding this exhibition, Khaled says: "It is true that amputees are everywhere, but a large portion of these victims are confined to their homes, reliving their physical and psychological pain, away from the eyes of others. This was the point I wanted to convey to everyone: to recognize that something we are unaware of can become a wound that makes us feel the pain of others."

 In addition to his solo work, Khaled has participated in several group exhibitions, including Colors from Gaza at the Walled-Off Hotel in Bethlehem in 2022, Gift Gallery at the Al-Mamal Foundation in 2021, Qalandia International at Shababeek Gallery in Gaza in 2018, Song of Stone at the YMCA in 2017, and On Jerusalem Road at Roots Gallery in Gaza in 2016. Khaled has also participated in numerous workshops and events both locally and internationally. These experiences have allowed him to continue pushing the boundaries of his artistic expression, refining his skills, and deepening his exploration of human emotion.

Khaled Hussein lost all his sculptures and paintings when his house was bombarded, along with additional artworks that were on display at Gallery 28 in Rafah.